Clomid (Clomiphene) is an oral medication that induces, or regulates, ovulation. Understanding how Clomid works is important to understanding how most fertility drugs effect ovulation. Clomid exerts its effects at the hypothalamus, the gland that signals the pituitary to produce FSH, LH, and estrogen. FSH products stimulate the ovaries directly and the response is dose related.


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Clomid competes for estrogen receptors causing the hypothalamus to "read" lower estrogen levels.  Healthy follicles produce estrogen which is monitored by the hypothalamus and FSH production is increased/decreased based upon estrogen levels. As estrogen levels increase, FSH production decreases. Conversely, lower estrogen levels cause an increase in FSH and subsequent follicular stimulation.

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Women, and men, who have a problem in having children, are often recommended Clomid therapy to overcome this problem. Anovulation occurs in a woman when an egg is not released from the ovaries into the fallopian tubes on a regular, monthly basis. Some women suffer from a Polycystic Ovarian Syndrome [PCOS] in which there is a cessation of periods, menses are irregular or there is heavy bleeding due to the presence of ovarian cysts, all of which prevent women from conceiving. Women who have taken Clomid have been known to give birth to twins, and even triplets, due to increased ovulation.

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Clomid is a small scored tablet of white color and round shape taken with a glass of water. It is taken in five day cycles. Normally six cycles are enough for the therapy under the condition of coitus happening in proper time. The treatment course should be started with the low dose and it shouldn’t be increased unless the patient has no ovulation while taking the low dose. Mostly one course of Clomid is quite enough to get ovulation.

To achieve the expected result the patient should stick to the schedule of tablets taking and avoid missing the dose. And if you follow the recommendations of the prescription label and observe how the tablets work by taking notes of your body condition, your chances to become pregnant become very high. Monitoring your health condition while taking any medication including Clomid is extremely important as physical condition of our bodies differ and their reaction to medical preparations too. If you observe any side effects contact your doctor, he may change the dose for the best result.